The aim of the study was to evaluate the effectiveness of the use of natural antioxidants on the state of endothelial function in patients with IHD and chronic heart failure (CHF). Sixty patients with IHD were examined. Stable exertional angina of FC II-III, complicated CHF, middle-aged from 45-60 years. It was found that the inclusion of tivortine in the complex therapy of patients with CHF can reduce the manifestations of vascular endothelial dysfunction, which indicates the promise of using the drug for the purpose of secondary prevention of coronary heart disease and CHF.

Chronic heart failure, endothelial function, antioxidants

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