The article examines the characteristics of oral fluid and mineral metabolism in patients with gastrointestinal diseases and biliary dysfunction. Particular attention is given to salivary pH, buffer capacity, calcium and phosphate levels, and the mineralizing potential of oral fluid as key factors determining enamel resistance to demineralization. Chronic gastrointestinal pathology may be associated with impaired digestion, altered absorption of minerals and fat-soluble vitamins, changes in intestinal microbiota, and systemic metabolic disturbances. Biliary dysfunction, including impaired bile secretion and biliary sludge formation, may additionally affect lipid digestion, bile acid metabolism, vitamin D-dependent calcium-phosphate regulation, and the biochemical conditions required for enamel and dentin mineral stability. The article substantiates the need for a comprehensive clinical and biochemical assessment of oral fluid in patients with gastrointestinal and biliary disorders in order to identify early risk factors for enamel demineralization, dental erosion, caries progression, and non-carious lesions [1; 5].

Oral fluid, saliva, salivary pH

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