Hybrid Learning Strategy for Healthcare Image Region Extraction Via Contrast-Informed Stochastic Propagation Techniques

Authors

  • Dr. Arvind Kumar Sharma Department of Computer Science, Institute of Medical Imaging Technology, India Author

Keywords:

Medical Image Segmentation, Semi-Supervised Learning, Contrastive Learning

Abstract

Accurate region extraction in medical imaging is a critical prerequisite for diagnostic decision-making, treatment planning, and disease monitoring. However, challenges such as limited annotated datasets, high intra-class variability, and imaging noise hinder the performance of conventional fully supervised segmentation models. This study proposes a hybrid learning strategy integrating contrast-informed representation learning with stochastic propagation mechanisms to improve region extraction in healthcare imaging. The framework combines semi-supervised learning paradigms, contrastive feature embedding, and probabilistic diffusion-based refinement to exploit both labeled and unlabeled data effectively.

The proposed methodology leverages contrastive learning to capture global and local feature dependencies, enabling robust representation under sparse annotations. A stochastic propagation module, inspired by diffusion probabilistic models, is incorporated to iteratively refine segmentation boundaries through uncertainty-aware pixel propagation. Additionally, pseudo-labeling and consistency regularization mechanisms are utilized to enhance generalization performance while mitigating label noise. The hybrid architecture integrates attention mechanisms and transformer-based encoders to further strengthen contextual understanding.

Experimental evaluations are conducted on benchmark datasets, including breast ultrasound and brain MRI segmentation collections. The proposed approach demonstrates superior performance in region delineation accuracy, boundary precision, and robustness to noise compared to traditional semi-supervised and fully supervised methods. The findings indicate that integrating contrastive representation learning with stochastic propagation significantly enhances segmentation reliability, particularly in low-data regimes.

This research contributes a novel hybrid framework that bridges deterministic and probabilistic learning strategies for medical image segmentation. It highlights the importance of uncertainty modeling and contrast-driven feature learning in improving healthcare imaging systems. The study also discusses the limitations related to computational complexity and scalability, providing insights for future research in adaptive hybrid learning architectures for medical imaging applications.

Downloads

Download data is not yet available.

References

Al-Dhabyani W, Gomaa M, Khaled H, and Fahmy A, “Dataset of breast ultrasound images,” Data Brief, vol. 28, Feb. 2020, Art. no. 104863.

Bakas S, “Advancing the cancer genome atlas glioma MRI collections with expert segmentation labels and radiomic features,” Sci. Data, vol. 4, no. 1, p. 113, 2017.

Calimeri F, Marzullo A, Stamile C, and Terracina G, “Biomedical data augmentation using generative adversarial neural networks,” in Proc. 26th Int. Conf. Artif. Neural Netw. Mach. Learn. (ICANN), 2017, pp. 626–634.

Chaitanya K, Erdil E, Karani N, and Konukoglu E, “Contrastive learning of global and local features for medical image segmentation with limited annotations,” in Proc. 34th Conf. Neural Inf. Process. Syst., vol. 33, 2020, pp. 12546–12558.

Chapelle O, Schlkopf B, and Zien A, “Semi-supervised learning,” IEEE Trans. Neural Netw., vol. 20, 2006.

Chen L, Chen Y, Xi J, and Le X, “Knowledge from the original network: Restore a better pruned network with knowledge distillation,” Complex Intell. Syst., vol. 8, pp. 709–718, Apr. 2022.

Chen L, You Z, Zhang N, Xi J, and Le X, “UTRAD: Anomaly detection and localization with u-transformer,” Neural Netw., vol. 147, pp. 53–62, Mar. 2022.

Chuquicusma M. J, Hussein S, Burt J, and Bagci U, “How to fool radiologists with generative adversarial networks? A visual turing test for lung cancer diagnosis,” in Proc. IEEE 15th Int. Symp. Biomed. Imag. (ISBI), 2018, pp. 240–244.

Cui W, “Semi-supervised brain lesion segmentation with an adapted mean teacher model,” in Proc. Int. Conf. Inf. Proc. Med. Imag., 2019, pp. 554–565.

Dorjsembe Z, Pao H. K, Odonchimed S, and Xiao F, “Conditional diffusion models for semantic 3D brain MRI synthesis,” IEEE J. Biomed. Health Inform., vol. 28, no. 7, pp. 4084–4093, Jul. 2024.

Dorjsembe Z, Pao H.-K, and Ao F, “Polyp DDPM: Diffusion-based semantic polyp synthesis for enhanced segmentation,” 2024, arXiv:2402.04031.

Goodfellow I, “Generative adversarial networks,” Commun. ACM, vol. 63, no. 11, pp. 139–144, 2020.

Han T, “Breaking medical data sharing boundaries by using synthesized radiographs,” Sci. Adv., vol. 6, no. 49, 2020, Art. no. eabb7973.

Ho J, Jain A, and Abbeel P, “Denoising diffusion probabilistic models,” in Proc. 34th Conf. Neural Inf. Process. Syst., vol. 33, 2020, pp. 6840–6851.

Kidder B. L, “Advanced image generation for cancer using diffusion models,” bioRxiv, Preprint, 2023.

Krause J, “Deep learning detects genetic alterations in cancer histology generated by adversarial networks,” J. Pathol., vol. 254, no. 1, pp. 70–79, 2021.

Lee D.-H, “Pseudo-label: The simple and efficient semi-supervised learning method for deep neural networks,” in Proc. Workshop Challenges Represent. Learn. (ICML), 2013, p. 896.

Loshchilov I, and Hutter F, “Decoupled weight decay regularization,” in Proc. Int. Conf. Learn. Represent., 2018, pp. 1–18.

Loshchilov I, and Hutter F, “SGDR: Stochastic gradient descent with warm restarts,” in Proc. Int. Conf. Learn. Represent., 2016, pp. 1–16.

Luo X, Chen J, Song T, and Wang G, “Semi-supervised medical image segmentation through dual-task consistency,” in Proc. AAAI Conf. Artif. Intell., 2021, pp. 8801–8809.

Saxena D, and Cao J, “Generative adversarial networks (GANs): Challenges, solutions, and future directions,” ACM Comput. Surv., vol. 54, no. 3, pp. 1–42, 2020.

Sohn K, “FixMatch: Simplifying semi-supervised learning with consistency and confidence,” in Proc. 34th Conf. Neural Inform. Process. Syst., 2020, pp. 596–608.

Wang W, Zhou T, Yu F, Dai J, Konukoglu E, and Gool L. V, “Exploring cross-image pixel contrast for semantic segmentation,” in Proc. IEEE/CVF Int. Conf. Comput. Vis., 2021, pp. 7283–7293.

Wang X, “SSA-Net: Spatial self-attention network for COVID-19 pneumonia infection segmentation with semi-supervised few-shot learning,” Med. Image Anal., vol. 79, Jul. 2022, Art. no. 102459.

Wu Z, Xiong Y, Yu S. X, and Lin D, “Unsupervised feature learning via non-parametric instance discrimination,” in Proc. IEEE Conf. Comput. Vis. Pattern Recognit., 2018, pp. 3733–3742.

Xie Q, Luong M. T, Hovy E, and Le Q. V, “Self-training with noisy student improves ImageNet classification,” in Proc. IEEE Conf. Comput. Vis. Pattern Recognit., 2020, pp. 10684–10695.

Yao H, Hu X, and Li X, “Enhancing pseudo label quality for semi-supervised domain-generalized medical image segmentation,” in Proc. AAAI Conf. Artif. Intell., 2022, pp. 3099–3107.

Zhang S, Zhang J, Tian B, Lukasiewicz T, and Xu Z, “Multi-modal contrastive mutual learning and pseudo-label re-learning for semi-supervised medical image segmentation,” Med. Image Anal., vol. 83, Jan. 2023, Art. no. 102656.

Zhu X, Cheng D, Zhang Z, Lin S, and Dai J, “An empirical study of spatial attention mechanisms in deep networks,” in Proc. IEEE/CVF Int. Conf. Comput. Vis., 2019, pp. 6687–6696.

Zhu Y, “Improving semantic segmentation via self-training,” 2020, arXiv:2004.14960.

“IXI dataset.” 2019. [Online]. Available: https://brain-development.org/ixi-dataset/

Downloads

Published

2026-04-01

How to Cite

Dr. Arvind Kumar Sharma. (2026). Hybrid Learning Strategy for Healthcare Image Region Extraction Via Contrast-Informed Stochastic Propagation Techniques. International Journal of Modern Medicine, 5(04), 1-6. https://intjmm.com/index.php/ijmm/article/view/150

Similar Articles

1-10 of 87

You may also start an advanced similarity search for this article.